Xanthohumol, CAS# 6754-58-1

Analysis method: HPLC 13cNMR、1HNMR、MS
Molecular formula: C21H22O5
Molecular weight: 354.4
CAS No.: 6754-58-1
Apperance: Yellow powder
Grade: 98%-99% （ HPLC ）
Packaging: As required.
Annual capacity: 1000 kgs
Storage condition: Refrigerate and protect from light.
Plant source: 啤酒花/Humulus lupulus Linn.

Xanthohumol belongs to the class of organic compounds known as 3-prenylated chalcones. These are chalcones featuring a C5-isoprenoid unit at the 3-position. Thus, xanthohumol is considered to be a flavonoid lipid molecule. Xanthohumol is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. Xanthohumol can be extracted with pressurized hot water. Xanthohumol is a bitter tasting compound. Outside of the human body, Xanthohumol is found, on average, in the highest concentration within beers. Xanthohumol has also been detected, but not quantified in, alcoholic beverages. This could make xanthohumol a potential biomarker for the consumption of these foods. In commercial beers, the concentration of xanthohumol ranges from about 2 μg/L – 1.2 mg/L. This molecule is extended three times with malonyl CoA, cyclized through a Claisen condensation, and aromatized through tautomerization to form naringenin chalcone (chalconaringenin). This compound is also found in beer and belongs to a class of compounds that contribute to the bitterness and flavor of hops. Xanthohumol is a prenylated chalconoid derived from a plant type III PKS, and is synthesized in the glandular trichromes of hop cones. Different hop varieties and different beers contain varying quantities of xanthohumol. In the case of xanthohumol, a prenyltransferase called Humulus lupulus prenyltransferase 1 (HlPT-1) attaches a molecule of dimethylallyl pyrophosphate from the DXP pathway. Total syntheses of xanthohumol and derivatives have been achieved, though extraction from hops remains a primary source.

——Source: HMDB

Xanthohumol is one of our superior products. Tauto Biotech successfully extracted 98%-99% （ HPLC ） Xanthohumol by utilizing our own patented extraction method(HSCCC). Related technology is applicable to production lines with a scale of ≥1000 kgs.

Advantages: continuous supply, strict QA, HSCCC technology, annual production capacity ≥1000 kgs.

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