Psoralen, CAS# 66-97-7

Analysis method: HPLC 13cNMR、1HNMR、MS
Molecular formula: C11H6O3
Molecular weight: 186.16354
CAS No.: 66-97-7
Apperance: White powder
Grade: 98%-99% （ HPLC ）
Packaging: As required.
Annual capacity: 100 kgs
Storage condition: Refrigerate and protect from light.
Plant source: 补骨脂/The seeds of Psoralea corylifolia Linn.

Psoralen, also known as psoralene, ficusin or manaderm, belongs to the class of organic compounds known as psoralens. These are organic compounds containing a psoralen moiety, which consists of a furan fused to a chromenone to for 7H-furo[3,2-g]chromen-7-one. Psoralen is the parent compound in a family of naturally occurring organic compounds known as the linear furanocoumarins. Psoralen is structurally related to coumarin by the addition of a fused furan ring and is considered as a derivative of umbelliferone. Biosynthetically, psoralen originates from coumarins in the shikimate pathway. Psoralen is produced exclusively by plants but can be found in animals that consume these plants. Psoralen can be found in several plant sources with Ficus carica (the common fig) being probably the most abundant source of psoralens. They are also found in small quantities in Ammi visnaga (bisnaga), Pastinaca sativa (parsnip), Petroselinum crispum (parsley), Levisticum officinale (lovage), Foeniculum vulgare (fruit, i.e., Fennel seeds), Daucus carota (carrot), Psoralea corylifolia (babchi), Apium graveolens (celery), and bergamot oil (bergapten, bergamottin). Psoralen is found in all citrus fruits. Psoralen is a well-known mutagen and is used for this purpose in molecular biology research. Psoralen intercalates into DNA and on exposure to ultraviolet (UVA) radiation can form monoadducts and covalent inter-strand cross-links (ICL) with thymines in the DNA molecule. Psoralen also functions as a drug. An important use of psoralen is in the treatment for skin problems such as psoriasis and, to a lesser extent, eczema and vitiligo. This treatment takes advantage of the high UV absorbance of psoralen. In treating these skin conditions psoralen is applied first to sensitise the skin, then UVA light is applied to clean up the skin problem. Psoralen has also been recommended for treating alopecia.

——Source: HMDB

Psoralen is one of our superior products. Tauto Biotech successfully extracted 98%-99% （ HPLC ） Psoralen by utilizing our own patented extraction method(HSCCC). Related technology is applicable to production lines with a scale of ≥100 kgs.

Advantages: continuous supply, strict QA, HSCCC technology, annual production capacity ≥100 kgs.

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Ingredients found in 补骨脂/The seeds of Psoralea corylifolia Linn.: