Biochanin A, CAS# 491-80-5

Analysis method: HPLC 13cNMR、1HNMR、MS
Molecular formula: C16H12O5
Molecular weight: 284.26
CAS No.: 491-80-5
Apperance: Yellow powder
Grade: 98%-99% （ HPLC ）
Packaging: As required.
Annual capacity: 1000 kgs
Storage condition: Refrigerate and protect from light.
Plant source: 红车轴草/Trifolium pratense L.

The phytoestrogen biochanin A is an isoflavone derivative isolated from red clover Trifolium pratense with anticarcinogenic properties. Treating MCF-7 human breast carcinoma cells with biochanin A alone caused the accumulation of CYP1A1 mRNA and an increase in CYP1A1-specific 7-ethoxyresorufin O-deethylase (EROD) activity in a dose dependent manner. Biochanin A may be a natural ligand to bind on aryl hydrocarbon receptor acting as an antagonist/agonist of the pathway. (PMID: 16903077 ). Biochanin A suppress nuclear factor-kappaB-driven interleukin-6 (IL6) expression. In addition to its physiologic immune function as an acute stress cytokine, sustained elevated expression levels of IL6 promote chronic inflammatory disorders, aging frailty, and tumorigenesis. (PMID: 16651441 ). Biochanin A induces a decrease in invasive activity of U87MG cells in a dose-related manner. (PMID: 16598420 ). Biochanin A activates peroxisome proliferator-activated receptors (PPAR) PPARalpha, PPARgamma, and adipocyte differentiation in vitro of 3T3-L1 preadipocytes, suggesting potential value of isoflavones, especially biochanin A and their parent botanicals, as antidiabetic agents and for use in regulating lipid metabolism. (PMID: 16549448 ).

——Source: HMDB

Biochanin A is one of our superior products. Tauto Biotech successfully extracted 98%-99% （ HPLC ） Biochanin A by utilizing our own patented extraction method(HSCCC). Related technology is applicable to production lines with a scale of ≥1000 kgs.

Advantages: continuous supply, strict QA, HSCCC technology, annual production capacity ≥1000 kgs.

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