Isorhamnetin, CAS# 480-19-3

Analysis method: HPLC 13cNMR、1HNMR、MS
Molecular formula: C16H12O7
Molecular weight: 316.26228
CAS No.: 480-19-3
Apperance: Yellow powder
Grade: 98%-99% （ HPLC ）
Packaging: As required.
Annual capacity: 25 kgs
Storage condition: Refrigerate and protect from light.
Plant source: 银杏叶/The leaves of Ginkgo biloba L.

Isorhamnetin is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. However, it is found in human plasma as conjugates with glucuronic acid, sulfate or methyl groups, with no significant amounts of free quercetin present. Isorhamnetin prevents endothelial cell injuries from oxidized LDL via inhibition of lectin-like ox-LDL receptor-1 upregulation, interference of ox-LDL-mediated intracellular signaling pathway (p38MAPK activation, NF-kappaB nuclear translocation, eNOS expression) and the antioxidant activity of isorhamnetin. Isorhamnetin prevents endothelial dysfunction, superoxide production, and overexpression of p47phox induced by angiotensin II. Isorhamnetin appears to be a potent drug against esophageal cancer due to its in vitro potential to not only inhibit proliferation but also induce apoptosis of Eca-109 cells. (PMID: 15493462 , 17368593 , 17374653 , 16963021 ).

——Source: HMDB

Isorhamnetin is one of our superior products. Tauto Biotech successfully extracted 98%-99% （ HPLC ） Isorhamnetin by utilizing our own patented extraction method(HSCCC). Related technology is applicable to production lines with a scale of ≥25 kgs.

Advantages: continuous supply, strict QA, HSCCC technology, annual production capacity ≥25 kgs.

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Ingredients found in 银杏叶/The leaves of Ginkgo biloba L.: